Wednesday, December 5, 2012

There Is Blood Under Boston's Streets

"Blood storage lab holds clues for disease prevention" by Deborah Kotz  |  Globe Staff, August 22, 2012

Deep beneath Commonwealth Avenue rests a freezer farm stocked with more than 2 million frozen vials of human blood. The samples, sitting ­under a convenience store and butting up against tunnels ­beneath the T’s Green Line, are chilled to 155 degrees ­below zero Fahrenheit as they reside in giant metal vats pumped full of liquid nitrogen.

The blood came from some 150,000 volunteers who participated in research studies conducted by Brigham and Women’s Hospital during the past two decades and serves as a trove for scientists endeavoring to answer some of the most vexing questions in medicine.

Researchers, for example, can dip into the blood samples repeatedly to analyze the DNA of study participants who ­developed cancer or heart disease years after the initial study ended. Their goal is to find new ways to prevent chronic illness and to determine which patients get the biggest benefits from a particular drug, potentially paving the way to tailor medical treatments to individual patients.

One of the more pressing items on their agenda: to provide proof that reducing artery-­damaging inflammation prevents heart attacks and strokes. To help answer that question, thousands of new blood samples will soon join those already in the freezer farm....

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Related: Police seek witness in South End shooting

That is some of the blood on Boston's streets.